Original Article

Authors:
Santiago Herrero, Natalia Mendoza, Marta Muñoz Rodríguez, Dolores Mendoza, Eva García Piney, Ana María Sanchez Prieto

Authors:
Geoffrey Paul Carden, Jonathan Wayne Graham, Stuart McLennan, Leo Anthony Celi

Authors:
Ross C. Freebairn, Margaret Monk, Arpan Mehta, Ankia Anderson

There are well over 50,000 patients who receive ventilation via an endotracheal tube in the Intensive Care Units (ICUs) in Australia and New Zealand every year. Almost all episodes of invasive ventilation in adults are associated with inflation of endotracheal cuff. While monitoring of the cuff pressure has been recommended during anaesthesia this has not been reflected in any of the minimum standards documents.

Authors:
Ricardo Fernández, Angel Galera ,William Rodríguez,Ernesto Rive Mora, Gloria Rodríguez-Vega

Sepsis is a clinical syndrome characterized by systemic inflammation and widespread tissue injury. It results from an excessive inflammatory host response to an infective agent which, when generalized, involves normal tissue not originally affected by the causative organism(s). There is massive release of inflammatory mediators, causing leukocytes to accumulate in organs distant from the initial infection, with further inflammation. Recent evidence recognizes the active role of a deregulated coagulation cascade in the pathophysiology of sepsis.

Authors:
Bobbak Vahid, Paul E. Marik, Joseph Varon

Jaundice following cardiac surgery, frequently referred to as “post-pump jaundice,” has been reported since the 1960’s with an incidence of between 3 to 40%. The incidence of jaundice following mitral valve replacement has been reported to be as high as 55%. Jaundice following cardiac surgery has been associated with prolonged mechanical ventilation, prolonged intensive care unit (ICU) stay, and a higher mortality. The causes of jaundice following cardiac surgery include acute cholecystitis, acute pancreatitis, shocked liver, and septic shock.

Article ID:
20061203224443
Authors:
Menaldi Rasmin

Study objective: to evaluate patients who came with the history of snoring with Berlin Questionnaire and sleep study using portable monitoring device. Setting: Mitra International Hospital, Jakarta, Indonesia. Material and methods: This was a preliminary study in 15 patients who came to the Respiratory Clinic with the history of snoring and suspicion of having obstructive sleep apnea (OSA). They were intended to undergo a sleep study using a portable device (PM).

Article ID:
20060726224735
Authors:
Siswanto BB, Sunanto, Munawar M, Kusmana D, Hanafiah A, Waspadji S, Bachtiar A

Objective. To look for predictors of mortality and rehospitalization, we conducted a prospective study using fifty variables from history, physical examination, ECG, CXR, Echocardiography and blood test (N Terminal proBNP, hsCRP, and lactate level) that suspected as predictors in heart failure Design. Blinded prospective cohort study Setting. Emergency room of Harapan Kita National Heart Center, Jakarta-Indonesia as entry site, with ICCU, wards, and OPD for evaluation. Patients population for study.

Article ID:
20060315222152
Authors:
Noha El Sakka, Helen F. Galley, Ola Sharaki, Myriam Helmy, Salah Marzouk, Shafik Azmy, Mona Sedrak, Nigel R. Webster

Aged neutrophils undergo spontaneous apoptosis and delayed apoptosis is associated with persistence of inflammatory disorders through release of toxic metabolites. We evaluated spontaneous apoptosis of neutrophils in patients with multiorgan dysfunction syndrome and neutrophil respiratory burst activity. Neutrophil apoptosis was assessed at study enrollment and after 24 hours incubation in culture medium by annexin-V assay, morphology and DNA fragmentation. Respiratory burst activity was measured using dihydrorhodamine.

Article ID:
20060115112032
Authors:
Kang H. Lee, Philippe Rico, Michael R. Pinsky

It is difficult clinically to measure relative blood flow to each lung. We hypothesized that uni-lung % blood flow is linearly related to % carbon dioxide excretion (VCO2). In a canine model of acute unilateral lung injury, we measured uni-lung flow with ultrasonic flow-probes, and uni-lung VCO2 with two separate metabolic monitors utilizing split lung ventilation following thoracotomy. Relative flow to the lungs was altered by inflating a pulmonary artery catheter balloon in one of the lungs under conditions of normal lung function and following induction of acute lung injury.