Review Article

Authors:
Alma Rivera, Joseph F. Dasta, Joseph Varon

Health care costs represent a large percentage of the gross domestic product all over the world. According to the National Health Statistics Group, health care expenditure in the United States accounted for as much as 14% of the gross national product in 1992 and it is projected to reach 30% by 2030.
The intensive care unit (ICU) represents the hallmark of highly competent modern hospitals, offering highly trained staff and life-saving technology and it is also one of the most expensive units in the hospital.

Authors:
Karina M. Soto-Ruiz, W. Frank Peacock

Endurance sports such as marathon running are increasingly popular, attracting both professional and recreational athletes. While most participants recognize that these events can result in health hazards, few consider death a likely outcome. Exercise associated hyponatremia can be a consequence for which fatal outcomes may occur. In some it is mild and without symptoms. However, in others it is of such severity that respiratory failure secondary to pulmonary edema, and possibly death may result.

Authors:
Yahya Shehabi, John A. Botha, David Ernest, Ross C. Freebairn, Michael Reade, Brigit L. Roberts, Ian Seppelt, Leonie Weisbrodt

Sedation and analgesia are common interventions in intensive care and constitute an integral part of the care of critically ill patients. However, there is no consensus on the best combination of agents or strategies to manage sedation and analgesia effectively and safely, and in particular in patients who need prolonged mechanical ventilation.

Authors:
Rudolph L. Koch, Peter J. Papadakos, Burkhart Lachmann

One of the most difficult organs to procure for donation is the lung. A detailed understanding of the physiology of mechanical ventilation and its effect on donor lungs is needed to impact on the outcome of lung transplantation. An organized protocol for mechanical ventilation management of the organ donor using the Open Lung Model may positively affect the number of organs that can be procured, and the function of these organs post transplant.

Authors:
Rodrigo Pedraza, Paul E. Marik, Joseph Varon

Authors:
Luciana B Sutanto, Salim Surani, Teddy OH Prasetyono, Embing Syamsudin, A Sugeng, Irawan Muhidin

Authors:
Rosángela L. Fernández-Medero, Angel Cestero-Ruiz, Ricardo H. Brau-Ramírez, William Rodríguez-Cintrón, Gloria Rodríguez-Vega

Authors:
Alaa Gouda, Abdullah Al-shimemeri, Yaseen Arabi

Authors:
Amyn Hirani, Rodrigo Cavallazzi, Anastasia Shnitser, Paul E. Marik

Airway pressure release ventilation (APRV) is a relatively new mode of ventilation that became commercially available in the United States in the mid-1990s. APRV differs fundamentally from that of conventional positive-pressure ventilation. Whereas conventional modes of ventilation begin the ventilatory cycle at a baseline pressure and elevate airway pressure to accomplish tidal ventilation, APRV commences at an elevated baseline pressure and follows with a deflation to accomplish tidal ventilation (Figure 1) [1].